Of note, when cultured in vitro these cells retain at least some of the molecular expression profile displayed in vivo ,.
Therefore, unveiling the mechanism of parasite cell attachment and tissue tropism is an important milestone to comprehend how the disease develops and progress.
For the cell binding assays, the endothelial cells were first returned to the quiescent state by culturing at 37°C for 48 h.
Significant enrichment of phage particles was also observed with the bladder and esophagus vasculature 213 and 123 times, respectively, relatively to fd-tet , and to a lesser extent, to skeletal muscle endothelium 40 times relative to fd-tet.