She also had a recurring role as Alexis Meade on the television series Ugly Betty.
If you're wondering who John Cusack's wife is, stop now - John Cusack has never married and does not have children! She is known for her role as Mystique in the trilogy of the X-Men film series, and as Joan from The Punisher 2004 , both of which are based on Marvel Comics.
But what is his love life like in real life? Her film credits include Halloween H20 1998 and She's All That 1999.
It's easy to be jealous of the women John Cusack has gone out with, so you'll have to try to contain your envy.